Efficacy of Antiviral Medications in Decreasing Inflammation Levels Among Covid-19 Patients Experiencing Chronic Kidney Disease (CKD)

Fendy Prasetyawan; Faisal Akhmal Muslikh; Anis Akhwan Dhafin; Elsa Mahardika Putri; Yuneka Saristiana; Susilo Margining Raharjo

doi:10.55927/cjas.v1i1.7037

Authors

Fendy Prasetyawan Universitas Kadiri
Faisal Akhmal Muslikh Institut Ilmu Kesehatan Bhakti Wiyata
Anis Akhwan Dhafin Universitas Kadiri
Elsa Mahardika Putri Universitas Kadiri
Yuneka Saristiana Universitas Kadiri
Susilo Margining Raharjo Universitas Kadiri

DOI:

https://doi.org/10.55927/cjas.v1i1.7037

Keywords:

Covid-19, Antiviral, Inflammation levels, Chronic Kidney

Abstract

Individuals with Chronic Kidney Disease (CKD) face an elevated risk of severe COVID-19 infection. A comprehensive investigation into the effectiveness of antiviral medications in treating COVID-19 patients is imperative. The primary goal is to assess the severity of the illness and the efficacy of antiviral drugs in individuals with COVID-19 and CKD following antiviral treatment at Dr. Soedomo Trenggalek Hospital. This study adopts a cross-sectional approach, employing purposive sampling for sample selection. Retrospective data from 2022 medical records of COVID-19 patients diagnosed with CKD are analyzed. The research findings highlight the efficacy of antiviral drugs in diminishing inflammation levels in COVID-19 patients, as indicated by a significant p-value of 0.000. However, the leukocyte data proved inadequate in determining the reduction in inflammatory levels. Therefore, obtaining data on C-reactive protein (CVR) and lymphocytes is crucial for a more accurate measurement. The p-value for ClCr is 0.842.

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