Antiseptic Activity of Combination Lotion of Herbal Extracts of Gotu Kola (Centella Asiatica (L). Urban) and Aloe Vera Against Psedomonas Aeruginosa Bacteria

Authors

  • Delladari Mayefis Institut Kesehatan Mitra Bunda
  • Rury Trisa Utami Institut Kesehatan Mitra Bunda
  • Mulyani Ardian Ningsih Institut Kesehatan Mitra Bunda

DOI:

https://doi.org/10.55927/fjsr.v2i9.4765

Keywords:

Pseudomonas Aeruginosa, Antiseptic, Single Extract, Combination Extract

Abstract

To test the antibacterial activity of antiseptic gel, a combination of gotu kola herb extract and aloe vera extract against pseudomonas aeruginosa bacteria. Experimentally using the well diffusion method with a combined concentration of gotu kola and aloe vera herbal extracts of 5%:5% (F IV), 7.5%:2.5% (F V), 7.5%:2.5% (F VI), with positive control using antic antiseptic. The antibacterial activity with the antiseptic combination of gotu kola and aloe vera herbal extracts against pseudomonas aeruginosa bacteria has a medium category inhibitory power of 18.06 mm. The data obtained was tested for normality using the Shapiro Wilk test followed by the One Way Anova test. Based on statistical tests using ANOVA, it shows that there is a significant difference between the average percentage values between groups (sig ≤ 0.05). The single lotion activity and antibacterial combination of gotu kola and aloe vera herbal extracts can inhibit the growth of pseudomonas aeruginosa bacteria

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References

Agoes, G., 2012, Sediaan Farmasi Likuida-Semisolida, Edisi 7, 154-160, ITB. Bandung

Ayumi. 2011. The effect of handwashing with water or soap on bacterial contamination of hands. USA: Mc Graw Hill Companies p 49-53

Azzahra, F., Hayati, M., Kes, M., Periodonsia, B., Baiturrahmah, F. K. G. U., Raya, J., Pass, B., Sei, K. M., Kunci, K., Menurut, I., Kesehatan, R., Kesehatan, K., & Kemenkes, R. I. (n.d.). 2018. Uji aktivitas ekstrak daun (Centella asiatica ( L ). Urban) Terhadap pertumbuhan Streptococcus mutans Masalah kesehatan gigi dan mulut saat ini Indonesia Pencegahan karies gigi dengan penggunaan karena terjadinya karies gigi sangat berkaitan masya. L, 9–19

Cappucino, J.G., dan Sherman, N, 2014. Manual Laboratorium Mikrobiologi, Cetakan 2014. Edisi ke-8. Penerbit Buku Kedokteran (EGC), Jakarta.

Ketchum, P.A.1998. Mikrobiology Concept and Applications. John Wileyand Son Inc, USA.

Listiyaningsih, Afit dan Rizal Maarif Rukmana. 2010. Potensi Antibakteri Ekstrak Etanolik Kulit Daun Lidah Buaya (aloe vera) Terhadap Bakteri Paeusomonas aeruginosa. Jakarta : Program Studi DIII Analis Kesehatan Fakultas Ilmu Kesehatan, Universitas Setia Budi

Marselia, S., Wibowo, M. A., & Arreneuz, S. (2015). Aktivitas Antibakteri Ekstrak Daun Soma ( Ploiarium alternifolium Melch ) Terhadap Propionibacterium acnes. Jurnal Kimia Khatulistiwa, 4(4), 72–82

Nurrosyidah, lif Hanifa,ddk. (2019) .Uji Aktivitas Antibakteri Sediaan Gel Ekstrak Etanol Pegagan (Centella asiatica L.) Terhadap Bakteri Staphylococcus aureus Secara IN Vitro. Sidoarjo : STIKES Rumah Sakit Anwar Medika

Rachmawati, F., Nuria, CM. 2011. Uji Aktivitas Antibakteri Fraksi Kloroform Ekstrak Etanol Pegagan (Centella asiatica) Serta Identifikasi Senyawa Aktifnya. Jurnal. Semarang: Fakultas Farmasi Universitas Hasyim.

Rachmawati, F., Nuria, CM. 2011. Uji Aktivitas Antibakteri Fraksi Kloroform Ekstrak Etanol Pegagan (Centella asiatica) Serta Identifikasi Senyawa Aktifnya. Jurnal. Semarang: Fakultas Farmasi Universitas Hasyim.

Rahmadani, Fitri. 2015 “Uji Aktivitas Antibakteri dari Ekstrak Etanol 96% Kulit Batang Kayu Jawa (Lannea coromandelica) Terhadap Bakteri Staphylococcus aureus, Escherichia coli, Helicobacter pylori, Pseudomonas aeruginosa”. Skripsi. Jakarta: Fakultas Kedokteran dan Ilmu Kesehatan UIN Syarif Hidayatullah,

Saeed, M., A., Ahmad, I., Yaqub, U., Akbar, S., Waheed, A., Saleem, M. dan Nasiruddin. 2004, Aloe vera : A Plant Of Vital Significance, Quarterly Science Vision.9(12), 1-13.

Widia,W. (2012). Formulasi Sediaan Gel ekstrak etanol daun lidah buaya (aloe vera L. ) sebagai anti jerawat dengan basis sodium alginate dan aktivitas antibakterinya terhadap staphylococus epidermis, skripsi, sarjana farmasi, muhammadiyah sukarta.

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Published

2023-09-30

How to Cite

Delladari Mayefis, Rury Trisa Utami, & Mulyani Ardian Ningsih. (2023). Antiseptic Activity of Combination Lotion of Herbal Extracts of Gotu Kola (Centella Asiatica (L). Urban) and Aloe Vera Against Psedomonas Aeruginosa Bacteria. Formosa Journal of Sustainable Research, 2(9), 2389–2400. https://doi.org/10.55927/fjsr.v2i9.4765